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Presentation

Presentation

Phase I Study of Selinexor, a Selective Inhibitor of Nuclear Export, in Combination with Fludarabine and Cytarabine in Children with Relapsed or Refractory Leukemia

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Presentation

Selinexor, a Selective Inhibitor of Nuclear Export (SINE), shows enhanced activity in combination with PD-1/PD-L1 blockade in syngeneic murine models of colon cancer and melanoma

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Presentation

ALS/FTD C9ORF72 hexanucleotide repeat expansion disrupts nucleocytoplasmic transport

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Nuclear pore abnormalities in C9ORF72 ALS iPSC neurons and tissue alter nucleocytoplasmic protein trafficking

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The role of nuclear export in TDP43-mediated neurodegeneration

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Targeting CRM1 in AML (Presented at ESH – Budapest)

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Selinexor Shows Marked Activity in Double-hit Diffuse Large B Cell Lymphoma (DLBCL) in Pre-clinical Models and in Patients with Heavily Pre-treated Relapsed/Refractory Double-hit DLBCL

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Preliminary Phase II Results of Ara-C and Idarubicin in Combination with Selective Inhibitor of Nuclear Export (SINE) Compound Selinexor (KPT-330) in Patients with Relapsed or Refractory AML

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Patients with Heavily Pretreated Diffuse Large B-Cell Lymphoma (DLBCL) Who Respond to Oral Selinexor Therapy Show Prolonged Survival: Updated Phase I Results

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A Phase 2 Study on Efficacy, Safety and Intratumoral Pharmacokinetics of Oral Selinexor (KPT-330) in Patients with Recurrent Glioblastoma (GBM)

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