Put Your Passion to Work

Join a team where everyone’s contribution makes a difference in the lives of patients and those who love them.



At Karyopharm you have an opportunity to do well by doing good. We challenge the norm. We disrupt. We innovate. We do things differently. We take this approach to serve patients with cancer and give them a chance to enjoy more of life’s precious moments.

Our Blueprint for Success

At Karyopharm we live by our ICURE values in order to provide access to novel therapies and ongoing support to patients living with cancer. This common value proposition allows us to work collaboratively, efficiently, and in sync as a global team with a singular focus on treatments that change lives.

  • Innovation

    We encourage employees to develop creative, yet practical ideas that don’t simply rely on things that have been done in the past.

  • Courage

    We challenge the norms to solve problems and advance science in order produce the best outcomes for patients.

  • Urgency

    We approach our tasks with drive, passion and dedication with an understanding that patients battling cancer are relying on us.

  • Resilience

    We remain committed to persevere even in the face of challenges and adversity.

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    We approach opportunities and tackle challenges with a great sense of enthusiasm and determination.

Our Statement on Diversity, Equity, and Inclusion

Karyopharm is committed to improving the lives of patients and those who love them by developing novel therapies to treat cancer and other rare diseases. The work we do is both inspiring and life-changing.  It requires the most diverse, the most unique, and the most authentic team in the industry. Karyopharmers are extremely innovative and we think differently. We are so proud of our global team who bring their broad range of expertise, experiences, languages, and backgrounds with them every day to do the work that is so clearly their passion. We are committed to diversity, equity, inclusion and belonging. We celebrate all forms of diversity (e.g. gender, gender identity, race, ethnicity, national origin, sexual orientation, differently-abled, veterans and so much more). It is our firm belief that this is a part of our strength and makes us uniquely suited to succeed in our ongoing commitment to employees, physicians, patients, and families alike.

Who We Are

Global Employees
Leadership Roles Held by Women
Identify as Part of a Minority Group
Headcount Growth Over the Past Year

Why work with us

Kristina Senior Director, Advocacy & Alliances

“My dream was to be able to advocate for patients in a stronger more innovative and inclusive way, and I was drawn to how Karyopharm encourages and supports creativity and innovation.”

Stephanie Senior Executive Assistant, R&D

I was excited to join a company with a mission to help patients, and liked the small business feel combined with a rapidly growing vision for the future. Cancer touches all of our lives, and I am inspired daily to work towards a treatment for all kinds of cancer at every stage. I am proud to be working for a company that is doing this work in the world.

Lingling Assistant Vice President, Biostatistics

Joining Karyopharm gave me the great learning opportunity to become an oncology statistician. I have experienced accelerated career development and plenty of opportunities to motivate myself and expand my comfort zones and skill set. It is extremely rewarding to know that my work is benefiting patients.

Kristina putting Urgency to action…shipping PPE to patients worldwide!
  • Health Benefits

    Peace of mind through best-in-class medical, dental, and vision benefits as well as the latest in Telemedicine and Virtual Reality.

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  • Supporting ALL Families, ALL the Time

    Families of all shapes, sizes and backgrounds are celebrated and supported through Care.com and Urbansitter memberships as well as tutoring services and primary and secondary caregiver leave as a cornerstone of the company’s offerings.

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  • Embrace Your Wellness

    Employees and Families have a range of needs and Karyopharm works to provide support in the form of fitness reimbursement, mindfulness programs, exercise classes and mental health programs.

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  • Partner in Prosperity

    Karyopharm offers a competitive 401k match with an immediate vest, an Employee Stock Purchase Program offering a 15% discount, and a total rewards program that includes programs for all employees at all stages of their careers

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Lets Talk

Like what you see but still have some questions about careers at Karyopharm? Click below for answers. We’re happy to put you in touch with the right person on the Karyopharm team to get the information that would be helpful.