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Presentation

Presentation

The Role of P21-Activated Kinase 4(PAK4) in Cancer Stemness & Epithelial-to-Mesenchymal Transition

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Presentation

KPT-9274 Inhibits Cellular NAD and Synergies with NAD Depleting Enzymes to Induce Cancer Cell Death

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Presentation

Selinexor, a Selective Inhibitor of Nuclear Export (SINE) Compound, Inhibits NF-κBActivity by Sequestering IκB-α in the Nucleus and Blocking IκB-α Degradation

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Presentation

In Vivo Efficacy of PAK4 Allosteric Modulator, KPT-9274, against a triple negative breast cancer model

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Presentation

Selective Inhibitor of Nuclear Export (SINE) compounds prevent migration and proliferation of Triple Negative Breast Cancer (TNBC) cells by restoring expression of ARRDC3

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Presentation

Synergistic Antitumor Effect of Selinexor, a Selective Inhibitor of Nuclear Export (SINE) Compound and Trastuzumab in a Mouse Model of Breast Cancer

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Selinexor, a Selective Inhibitor of Nuclear Export (SINE) Compound, Shows Synergistic Anti-­tumor Activity when Combined with PD-­1 Blockade in a Mouse Model of Colon Cancer

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Synergistic Antitumor Effect of Selinexor, a Selective Inhibitor of Nuclear Export (SINE) Compound and Panobinostat in a Mouse Model of Multiple Myeloma

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Selinexor, a Selective Inhibitor of Nuclear Export (SINE) Compound Shows Enhanced Anti-­tumor Activity When Combined with Either Venetoclax or Bendamustine in Diffuse Large B Cell Lymphoma (DLBCL) Mouse Models

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Presentation

KPT-8602 is a second-generation XPO1 inhibitor with improved in vivo tolerability that demonstrates potent acute lymphoblastic leukemia activity

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