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Presentation

Presentation

A Phase 1b Study with Selinexor, a First in Class Selective Inhibitor of Nuclear Export (SINE) in Patients with Advanced Sarcomas: An Efficacy Analysis

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Presentation

Preliminary Phase II Results of Selinexor (KPT-­‐330), an Oral Selective Inhibitor of Nuclear Export, in Patients with Heavily Pretreated Gynecological Cancers

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Presentation

PAK4 allosteric modulators (PAMs) repress the Wnt/?-catenin signaling pathway and tumor growth

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Selinexor, a selective inhibitor of nuclear export (SINE), acts through NF-?B deactivation and combines with proteasome inhibitors to synergistically induce tumor cell death

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Presentation

Selinexor, a selective inhibitor of nuclear export (SINE) compound, shows enhanced antitumor activity in combination with the PARP inhibitor, olaparib, in models of triple-negative breast cancer

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Presentation

Selinexor and melphalan combination therapy for the treatment of multiple myeloma

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Inhibition of Pak4 blocks growth of breast cancer cells

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Selective inhibitor of nuclear exporter CRM1/XPO1, Selinexor (KPT-330), exhibits remarkable activity against AML leukemia-initiating cells while sparing normal hematopoietic cells

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Selinexor (KPT-330) radio-sensitizes non-small cell lung cancer cells in vitro and in vivo

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Inhibition of PAK4 attenuates renal cell carcinoma (RCC) growth

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