Put Your Passion to Work

Join a team where everyone’s contribution makes a difference in the lives of patients and those who love them.


At Karyopharm you have an opportunity to do well by doing good. We challenge the norm. We disrupt. We innovate. We do things differently. We take this approach to serve patients with cancer and give them a chance to enjoy more of life’s precious moments.


Our Blueprint for Success

At Karyopharm we live by our ICARE values in order to provide access to novel therapies and ongoing support to patients living with cancer. This common value proposition allows us to work collaboratively, efficiently, and in sync as a global team with a singular focus on treatments that change lives.

  • Innovation

    We challenge the status quo when the current thinking no longer provides the best solution for our patients. We innovate with purpose and draw from diverse experiences.

  • Courage

    We pursue excellence and empower our collaborative teams to speak the truth and act boldly and compliantly with integrity, as we set and exceed clear and ambitious expectations.

  • Alignment & Accountability

    Together as One Karyopharm we deliver results that support a culture of networked teams that work together and drive results in service of patients.

  • Resilience

    We prioritize a culture of adaptability. Our teams not only celebrate successes, but also overcome obstacles and move forward.

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    We approach our work with passion and dedication.

Our Statement on Diversity, Equity, and Inclusion

Karyopharm is committed to improving the lives of patients and those who love them by developing novel therapies to treat cancer and other rare diseases. The work we do is both inspiring and life-changing.  It requires the most diverse, the most unique, and the most authentic team in the industry. Karyopharmers are extremely innovative and we think differently. We are so proud of our global team who bring their broad range of expertise, experiences, languages, and backgrounds with them every day to do the work that is so clearly their passion. We are committed to diversity, equity, inclusion and belonging. We celebrate all forms of diversity (e.g. gender, gender identity, race, ethnicity, national origin, sexual orientation, differently-abled, veterans and so much more). It is our firm belief that this is a part of our strength and makes us uniquely suited to succeed in our ongoing commitment to employees, physicians, patients, and families alike.

Our Statement on Equal Employment Opportunity

Karyopharm Therapeutics Inc. (the “Company”) is an equal opportunity employer. All qualified applicants will be considered without regard to age, race, color, sex, religion/creed, national origin, marital status, ancestry, citizenship, military, reservist or veteran status, pregnancy, sexual orientation or preference, gender identity, gender expression, physical or mental disability, genetic predisposition or carrier status, or any other category protected under applicable federal, state or local law. Consistent with its obligations under applicable law, the Company will make reasonable accommodations for qualified individuals with disabilities. If you require an accommodation in the application process, please contact a member of the Company’s Human Resources department.

Why work with us

Shijie VP, Data Sciences – Biostatistics

“As the VP of Data Sciences, the role of my team and of myself is to advance Karyopharm drug discovery and development programs by utilizing our knowledge in data. Throughout my four years at the company, I have been able to work on all of our clinical studies and regulatory submissions. These types of opportunities to help patients with unmet medical needs makes me realize that my work is so meaningful and so important.”

Stephanie Senior Executive Assistant, R&D

I was excited to join a company with a mission to help patients, and liked the small business feel combined with a rapidly growing vision for the future. Cancer touches all of our lives, and I am inspired daily to work towards a treatment for all kinds of cancer at every stage. I am proud to be working for a company that is doing this work in the world.

  • Health Benefits

    Peace of mind through best-in-class medical, dental, and vision benefits as well as the latest in Telemedicine and Virtual Reality.

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  • Supporting ALL Families, ALL the Time

    Families of all shapes, sizes and backgrounds are celebrated and supported through Care.com and Urbansitter memberships as well as tutoring services and primary and secondary caregiver leave as a cornerstone of the company’s offerings.

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  • Embrace Your Wellness

    Employees and Families have a range of needs and Karyopharm works to provide support in the form of fitness reimbursement, mindfulness programs, exercise classes and mental health programs.

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  • Partner in Prosperity

    Karyopharm offers a competitive 401k match with an immediate vest, an Employee Stock Purchase Program offering a 15% discount, and a total rewards program that includes programs for all employees at all stages of their careers

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Lets Talk

Like what you see but still have some questions about careers at Karyopharm? Click below for answers. We’re happy to put you in touch with the right person on the Karyopharm team to get the information that would be helpful.